Source: University of British Columbia http://www.publicaffairs.ubc.ca/media/releases/2006/mr-06-107.html UBC Biotech Partnership Produces Implantable Device, Earns National Innovation AwardOctober 18, 2006 A University of British Columbia industry collaboration that produced a therapeutic device implanted in more than two million coronary heart disease patients has earned a Synergy Award for Innovation from the Natural Sciences and Engineering Research Council (NSERC). The partnership between Angiotech Pharmaceuticals Inc. and UBC is one of seven national collaborations honoured with a $25,000 NSERC research grant. "We are delighted to see that the huge impact that this research has had on the lives of millions of people is being recognized with this prestigious award," says Angus Livingstone, managing director of UBC’s University Industry Liaison Office. "It is a great example of how UBC research can have real-life applications and be the basis of highly successful partnerships with industry." A collaboration started in 1992 between UBC Pharmaceutical Sciences Prof. Helen Burt -- an expert in drug delivery systems -- and Dr. William Hunter, Angiotech President and CEO, produced a drug-loaded coronary stent. Stents are surgically implanted cylindrical wire devices that support and keep open blood vessel walls. However, they can damage vessels and trigger a wound-healing response that results in overgrowth of blood vessels and tissue that narrows the vessel again. The process is known as restenosis. Hunter had a research interest in diseases involving angiogenesis, or formation of new blood vessels. Burt, and her lab team led by John Jackson, developed methods of encapsulating paclitaxel -- a drug that inhibits angiogenesis -- into biomaterials to form coatings and implants. Their collaboration led to a prototype paclitaxel-coated stent. In the first 18 months after the launch of TAXUS®, a paclitaxel-loaded stent that prevents restenosis, in the U.S., the product was implanted in more than two million patients. The continuing partnership between Burt and Angiotech has led to development of several other controlled release drug delivery systems, with 43 patents in 26 countries. The UILO guides breakthrough UBC research to market. UBC investigators conducted almost 6,900 projects and attracted more than $485 million in funding from various sources in 2005 / 06.There were 60 patents issued to UBC inventions in 2005 / 06, and the University received $16 million in technology licensing revenue. UBC is consistently ranked among the world’s 40 best universities, one of only two Canadian universities in this category. It is ranked within the top 10 North American universities, and first among Canadian universities, in terms of the number of U.S. life sciences patents. Angiotech Pharmaceuticals Inc. is a global specialty pharmaceutical and medical device company with 14 facilities in 6 countries and over 1,500 dedicated employees. NSERC is a federal agency that supports some 22,000 university students and postdoctoral fellows in their advanced studies, funds more than 10,000 university professors every year and fosters innovation by encouraging more than 800 Canadian companies to participate and invest in university research projects. For more information on the NSERC awards, visit www.nserc-crsng.gc.ca. - 30 - - - - Contact Hilary Thomson UBC Public Affairs Tel: 604.822.2644 Cell: 604.209.3048 E-mail: hilary.thomson@ubc.ca -
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